Failure is an Orphan (Let's Adopt)
نویسندگان
چکیده
منابع مشابه
Last Words: Failure is an Orphan (Let's Adopt)
We like to think that the progress of science follows an exponential curve, boldly shooting upwards, ever more speedily. In reality, there is a firmament of darkness (that’s our daily slog) sparsely spottedwith dim lights (those are discoveries). Fittingly, discoverers are also few, just as in every field of human endeavor. For every great leader, artist, or scientist there is a multitude of fo...
متن کاملSome Numbers behind Canada's Decision to Adopt an Orphan Drug Policy: US Orphan Drug Approvals in Canada, 1997–2012
We examined whether access to US-approved orphan drugs in Canada has changed between 1997 (when Canada chose not to adopt an orphan drug policy) and 2012 (when Canada reversed its policy decision). Specifically, we looked at two dimensions of access to US-approved orphan drugs in Canada: (1) regulatory access; and (2) temporal access. Whereas only 63% of US-approved orphan drugs were granted re...
متن کاملClozapine: is now the time for more clinicians to adopt this orphan?
Although many patients with schizophrenia fail to respond adequately to trials of 2 or more antipsychotics, utilization of clozapine for these patients remains low, despite recommendations for its use by accepted treatment guidelines. Some experts estimate that 5-10 times more patients could benefit from clozapine than who are now receiving it. Learning how to manage the unique side effect prof...
متن کاملAdopt IP Protections to ensure Regulatory exclusivity for Orphan Drugs
orphan drugs present unique risks — the potential return on investment is inherently constrained by small patient populations and attendant reimbursement challenges. recognizing these challenges, some countries have passed laws designed to make the economic model associated with developing treatments for orphan diseases more attractive. the most meaningful incentive provided by the various orph...
متن کاملIs BL Lacertae an “orphan” AGN?*
Aims. We have analysed optical spectra of BL Lacertae, the prototype of its blazar subclass, to verify the broad Hα emission line detected more than a decade ago and its possible flux variation. We used the spectroscopic information to investigate the question of the BL Lacertae parent population. Methods. Lowand high-resolution optical spectra of BL Lacertae were acquired with the DOLORES spec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Computational Linguistics
سال: 2010
ISSN: 0891-2017,1530-9312
DOI: 10.1162/coli.2010.36.1.36106